Showing posts with label kawasaki disease. Show all posts
Showing posts with label kawasaki disease. Show all posts

Saturday, December 29, 2018

Is kawasaki disease a lifelong disease?

Is kawasaki disease a lifelong disease?

Is kawasaki disease a lifelong disease?
Is kawasaki disease a lifelong disease?

@healthbiztips by Arlene Gentallan

Kawasaki disease is not a lifelong disease, but this disease can leave complications individuals bear for the rest of their lives. In fact, kawasaki disease is the leading cause of acquired heart disease among children.

Kawasaki disease is characterized by inflammation of blood vessels throughout the entire body. Without prompt treatment, this disease is life-threatening.

Complications of kawasaki disease includes:

  • aneurysm -- weakening and bulging of blood vessel wall which can potentially rupture (causing internal bleeding and blockage of blood flow)
  • dysrhythmia --irregar heart rythm
  • myocarditis -- inflammation of the heart
  • vasculitis -- inflammation of blood vessels


Sunday, December 23, 2018

Is Corticosteroid Bad for Kawasaki Disease?

Is Corticosteroid Bad for Kawasaki Disease?

Corticosteroid or steroid is use to treat patients with kawasaki disease when conventional treatment using intravenous immunoglobulin is ineffective.

In kawasaki disease, their is an inflammation of blood vessels throughout the body. Without prompt treatment, threatening cardiovascular complications can arise. This illness usually affects children and is the leading cause of heart disease among this young age group.

Is Corticosteroid Bad for Kawasaki Disease?
Is Corticosteroid Bad for Kawasaki Disease?

@healthbiztips by Arlene Gentallan

Studies have conflicting results.

There are studies that reveal using corticosteroid (steroid) is beneficial to children with kawasaki disease as it decreases the risk of cardiovascular complication. Using corticosteroid decreases the duration of symptom of kawasaki disease and speeds up normalization of laboratory tests results such as c-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).

The use of corticosteroid to treat kawasaki disease promotes faster recovery from the disease, thereby reducing hospital stay.

However, there are studies linking the use of corticosteroid to the increase the risk of developing aneurysm. Aneurysm is the bulging of artery due to weakness of the arterial wall which poses danger because it has a risk of rupturing which can lead to internal bleeding and blockage.

Corticosteroid to treat kawasaki disease is usually use as a last resort when conventional treatments fail to cure the disease, considering the fact that when kawasaki disease is left untreated, life threatening complications can arise.

However, other studies show that using corticosteroid to treat kawasaki disease is well tolerated and effective both as a first line treatment and as a last resort when conventional treatment fails to work.


The use of corticosteroid to treat kawasaki disease should be used with caution, taking into account both risks and benefits.

Resources:

Wardle AJ, Connolly GM, Seager MJ, Tulloh RM. Corticosteroids for the treatment of Kawasaki disease in children. Cochrane Database Syst Rev. 2017;1:CD011188. Published 2017 Jan 27. doi:10.1002/14651858.CD011188.pub2

Dhanrajani A, Yeung RSM. Revisiting the role of steroids and aspirin in the management of acute Kawasaki disease. Curr Opin Rheumatol. 2017;29(5):547-552.

Yang TJ, Lin MT, Lu CY, et al. The prevention of coronary arterial abnormalities in Kawasaki disease: A meta-analysis of the corticosteroid effectiveness. J Microbiol Immunol Infect. 2017;51(3):321-331.

Zhao CN, Du ZD, Gao LL. Corticosteroid Therapy Might be Associated with the Development of Coronary Aneurysm in Children with Kawasaki Disease. Chin Med J2016;129:922-8.

Sunday, December 9, 2018

21 Facts about Kawasaki Disease

High grade fever (40 degrees Celsius or higher) for over 4 days that's unresponsive to paracetamol and ibuprofen is usually the first sign of kawasaki disease. Most parents are not familiar with this disease because it is very rare. However, without treatment, this is a fatal illness that's a leading cause of acquired heart disease in children.

21 Facts about Kawasaki Disease
21 Facts about Kawasaki Disease

@healthbiztips by Arlene Gentallan

1. Kawasaki disease is a rare illness that commonly affects children under 5 years of age.

2. Having an Asian descent (specially Japanese and Korean) increases the chance of developing kawasaki disease.

3.The cause of kawasaki disease is unknown.

4. Kawasaki disease is also known as mucocutaneous lymph node syndrome.

5. Kawasaki disease is not contagious.

6. Kawasaki disease is identified in the year 1967 and is named after the Japanese pediatrician Dr. Tomisaku Kawasaki.

7. Kawasaki disease occurs worldwide, but Japan has higher incidence of this disease.

8. Localized outbreaks of kawasaki disease usually occurs in the winter and spring.

9. Males are two times more likely to get this disease.

10. In kawasaki disease,  the walls of blood vessels becomes inflammed and weak which can lead to potentially fatal complications such as aneurysm, in which the weakened blood vessel bulges and can potentially rupture.

11. Kawaski disease can involve any type of blood vessels such as arteries, capillaries, and viens.

12. Early signs and symptoms of kawasaki disease includes:

  • high fever lasting more than 5 days that is unresponsive to paracetamol and ibuprofen
  • redness of the eye
  • red, dry, and cracked lips
  • shiny red swollen tongue (also called "strawberry tongue")
  • irritation of the throat
  • swollen lymph nodes, usually at the neck
  • rash on the chest, abdomen, limbs, and groin
  • red and swollen palms of the hand and soles of the feet

13. After about 2 weeks after the onset of fever, late sign and symptoms develops including:

  • peeling of the skin of the hands and feet
  • joint pain
  • abdominal pain
  • vomiting
  • diarrhea

14. There is no prevention for kawasaki disease.

15. There is no single test to diagnose kawasaki disease. Doctors base their diagnosis on the patient's signs and symptoms.

16. Because of the risk of heart involvement, doctors may prescribe an echocardiogram test.

17. With prompt treatment, full recovery from kawasaki disease is possible and complications are rare.

18. Common medical treatment for kawasaki disease includes aspirin and intravenous immunoglobulin (antibodies).

19. Without prompt treatment, kawasaki disease is fatal.

20. Complications of kawasaki disease includes aneurysm, myocarditis, vasculitis, and dysrhythmia.

21. Recurrence of kawasaki disease is rare.